Sarah, a struggling young woman living in Brooklyn, agrees to volunteer as an Sarah, a struggling young woman living in Brooklyn, agrees to volunteer as an experimental subject for a pharmaceutical company called Dynamic Health Cure to be the bearer of LEXX and make money to solve her financial troubles and take care of her mother who has Alzheimer's. A nano chip is planted into her cerebral cortex and designed to take control of the body in order to contain diseases as soon as they occur. But when the implant with artificial intelligence turns sinister and orders her to commit crimes, Sarah is plunged into a murderous spiral with only one choice: to live or die.
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